Systemic sclerosis – multidisciplinary disease: clinical features and treatment
Identifieur interne : 000407 ( Main/Exploration ); précédent : 000406; suivant : 000408Systemic sclerosis – multidisciplinary disease: clinical features and treatment
Auteurs : Piotr Sobolewski [Pologne] ; Maria Ma Li Ska [Pologne] ; Marta Wieczorek [Pologne] ; Zuzanna Łagun [Pologne] ; Aleksandra Malewska [Pologne] ; Marek Roszkiewicz [Pologne] ; Raman Nitskovich [Pologne] ; El Bieta Szyma Ska [Pologne] ; Irena Walecka [Pologne]Source :
- Reumatologia [ 0034-6233 ] ; 2019.
Abstract
Systemic sclerosis is a chronic autoimmune disease of still not fully understood pathogenesis. Fibrosis, vascular wall damage, and disturbances of innate and acquired immune responses with autoantibody production are prominent features. Systemic sclerosis has specific subsets with different autoantibodies, and differences in the affected skin areas. The suspicion of systemic sclerosis and establishing the diagnosis will be facilitated by the criteria created by EULAR/ACR experts. The treatment of this autoimmune disease remains a challenge for clinicians and new therapeutic options are constantly sought. The occurrence of various symptoms and the involvement of many organs and systems make systemic sclerosis a multidisciplinary disease and require a holistic approach. The present article summarizes different clinical features of systemic sclerosis and the profile of autoantibodies and discusses recent rules and future perspectives in disease management.
Url:
DOI: 10.5114/reum.2019.87619
PubMed: 31548749
PubMed Central: 6753596
Affiliations:
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Hospital of the Ministry of the Interior, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Clinic of Dermatology, Centre of Postgraduate Medical Education, Central Clinical Hospital of the Ministry of the Interior, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Walecka, Irena" sort="Walecka, Irena" uniqKey="Walecka I" first="Irena" last="Walecka">Irena Walecka</name><affiliation wicri:level="1"><nlm:aff id="aff0001">Clinic of Dermatology, Centre of Postgraduate Medical Education, Central Clinical Hospital of the Ministry of the Interior, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Clinic of Dermatology, Centre of Postgraduate Medical Education, Central Clinical Hospital of the Ministry of the Interior, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author></analytic><series><title level="j">Reumatologia</title><idno type="ISSN">0034-6233</idno><idno type="eISSN">2084-9834</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Systemic sclerosis is a chronic autoimmune disease of still not fully understood pathogenesis. Fibrosis, vascular wall damage, and disturbances of innate and acquired immune responses with autoantibody production are prominent features. Systemic sclerosis has specific subsets with different autoantibodies, and differences in the affected skin areas. The suspicion of systemic sclerosis and establishing the diagnosis will be facilitated by the criteria created by EULAR/ACR experts. The treatment of this autoimmune disease remains a challenge for clinicians and new therapeutic options are constantly sought. The occurrence of various symptoms and the involvement of many organs and systems make systemic sclerosis a multidisciplinary disease and require a holistic approach. The present article summarizes different clinical features of systemic sclerosis and the profile of autoantibodies and discusses recent rules and future perspectives in disease management.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Furue, M" uniqKey="Furue M">M Furue</name></author><author><name sortKey="Mitoma, C" uniqKey="Mitoma C">C Mitoma</name></author><author><name sortKey="Mitoma, H" uniqKey="Mitoma H">H Mitoma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Clements, Pj" uniqKey="Clements P">PJ Clements</name></author><author><name sortKey="Hurwitz, El" uniqKey="Hurwitz E">EL Hurwitz</name></author><author><name sortKey="Wong, Wk" uniqKey="Wong W">WK Wong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kowal Bielecka, O" uniqKey="Kowal Bielecka O">O Kowal-Bielecka</name></author><author><name sortKey="Kuryliszyn Moskal, A" uniqKey="Kuryliszyn 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Gahlemann</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Pologne</li></country></list><tree><country name="Pologne"><noRegion><name sortKey="Sobolewski, Piotr" sort="Sobolewski, Piotr" uniqKey="Sobolewski P" first="Piotr" last="Sobolewski">Piotr Sobolewski</name></noRegion><name sortKey="Lagun, Zuzanna" sort="Lagun, Zuzanna" uniqKey="Lagun Z" first="Zuzanna" last="Łagun">Zuzanna Łagun</name><name sortKey="Ma Li Ska, Maria" sort="Ma Li Ska, Maria" uniqKey="Ma Li Ska M" first="Maria" last="Ma Li Ska">Maria Ma Li Ska</name><name sortKey="Malewska, Aleksandra" sort="Malewska, Aleksandra" uniqKey="Malewska A" first="Aleksandra" last="Malewska">Aleksandra Malewska</name><name sortKey="Nitskovich, Raman" sort="Nitskovich, Raman" uniqKey="Nitskovich R" first="Raman" last="Nitskovich">Raman Nitskovich</name><name sortKey="Roszkiewicz, Marek" sort="Roszkiewicz, Marek" uniqKey="Roszkiewicz M" first="Marek" last="Roszkiewicz">Marek Roszkiewicz</name><name sortKey="Szyma Ska, El Bieta" sort="Szyma Ska, El Bieta" uniqKey="Szyma Ska E" first="El Bieta" last="Szyma Ska">El Bieta Szyma Ska</name><name sortKey="Walecka, Irena" sort="Walecka, Irena" uniqKey="Walecka I" first="Irena" last="Walecka">Irena Walecka</name><name sortKey="Wieczorek, Marta" sort="Wieczorek, Marta" uniqKey="Wieczorek M" first="Marta" last="Wieczorek">Marta Wieczorek</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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